Neuroscience Fourth Edition (Sinauer Associates, 2008) p. 203:
Despite the substantial advances in understanding the cellular and molecular bases of some forms of plasticity, how selective changes of synaptic strength encode memories or other complex behavioral modifications in the mammalian brain is simply not known.
Synaptic computation underlying probabilistic inference, by Alireza Soltani and Xia-Jing Wang (Nature Neuroscience, Vol. 13, N. 1, Jan 2010, p. 112):
Little is known about the neural computations underlying this cognitive ability of probabilistic reasoning.
The problem is clearly stated.
Bertrand du Castel
Despite the substantial advances in understanding the cellular and molecular bases of some forms of plasticity, how selective changes of synaptic strength encode memories or other complex behavioral modifications in the mammalian brain is simply not known.
Synaptic computation underlying probabilistic inference, by Alireza Soltani and Xia-Jing Wang (Nature Neuroscience, Vol. 13, N. 1, Jan 2010, p. 112):
Little is known about the neural computations underlying this cognitive ability of probabilistic reasoning.
The problem is clearly stated.
Bertrand du Castel

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